I am a working in

I need an animal-free hydrogel to grow and is

I need my gel

Matrix Bio

Accelerating Discovery to Clinical Introduction

Matrix Bio empowers researchers to engineer exceptional hydrogels using robust prediction algorithms and AI-guided design suggestions

I am a working in

I need an animal-free hydrogel to grow and is

I need my gel

Matrix Bio

Revolutionizing 3D Cell Culture for Life Science Research & Development

Unprecedented Control Over Cell Culture in 3D:
Accelerating Discovery to Clinical Introduction

Our Mission

At Matrix Bio, our mission is to enable life science research and development from discovery through clinical introduction by providing scientists with unprecedented control over cell culture in 3D using design software to accelerate hydrogel development.

Our Mission

At Matrix Bio, our mission is to enable life science research and development from discovery through clinical introduction by providing scientists with unprecedented control over cell culture in 3D. Based in the Babraham Accelerator in Cambridge, our team of experts is committed to driving innovation in the field of 3D cell culture.

Our Platform

Matrix Bio is building a groundbreaking platform that radically increases the speed and scale of 3D cell culture development and discovery. Our proprietary technology combines novel high-throughput hydrogel engineering and screening techniques with advanced computational tools, creating a powerful design loop that allows us to rapidly optimize hydrogel formulations for 3D cell growth and develop new design tools for researchers and industry.

Our Approach

Our unique approach harnesses the power of high-throughput hydrogel engineering and computational tools to generate highly optimized hydrogel formulations for the growth of cells in 3 dimensions.
By creating a seamless integration between hydrogel design, synthesis, and characterization, we can quickly identify the ideal conditions for a wide range of cell types and applications. These large datasets inform our tools which we make available to researchers.

Our Approach

Our unique approach harnesses the power of high-throughput hydrogel engineering and computational tools to generate highly optimized hydrogel formulations for the growth of cells in 3 dimensions.
By creating a seamless integration between hydrogel design, synthesis, and characterization, we can quickly identify the ideal conditions for a wide range of cell types and applications.

Our Impact

Matrix Bio's cutting-edge platform is poised to revolutionize the life science industry by:

  • Accelerating drug discovery and development

  • Facilitating personalized medicine and targeted therapies

  • Advancing tissue engineering and regenerative medicine

  • Enhancing materials science and hydrogel research

Our Impact

Matrix Bio's cutting-edge platform is poised to revolutionize the life science industry by:

  • Accelerating drug discovery and development

  • Facilitating personalized medicine and targeted therapies

  • Advancing tissue engineering and regenerative medicine

  • Enhancing materials science and hydrogel research

Join Us

Matrix Bio

Contact us to learn more about our platform and software, partnership and licensing opportunities, and how we can help your organization unlock the full potential of 3D cell culture.

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Contact Us

chris@matrixs.bio

Revolutionise Cell Reprogramming with Optimised Microenvironments

Revolutionise Cell Reprogramming with Optimised Microenvironments

Viral delivery enables reprogramming somatic cells into pluripotent stem cells, unlocking revolutionary potential for regenerative medicine and drug discovery. However, current techniques face major limitations:

  • Extremely low reprogramming efficiency (~1%) restricts applications

  • Undefined culture microenvironments poorly recapitulate native niches

  • Marginal iterative improvements despite intense R&D efforts

  • Safety concerns around genomic integration

At Matrix Bio, we overcome these constraints through integrated automation, proprietary hydrogel engineering, and machine learning to recreate the extracellular complexity directing cell fate transitions.

Our automated microfluidics rapidly screens thousands of 3D hydrogel formulations to identify matrices that enhance reprogramming yield and control lineage trajectories.Powerful algorithms discern optimal combinations of architectural, mechanical and bioactive cues from these vast datasets.

The key advantages our platform offers include:

  • 10x increased reprogramming efficiency

  • Defined matrix composition and signalling complexity missing from standard 2D culture underlies improved performance.

  • Accelerated development timelines

  • High-throughput automated workflows enable systematic hydrogel optimization 100x faster than iterative approaches

  • Enhanced scale and safety

Our scaffolds can be fabricated at commercial scales using approved input materials and synthesise protocols. No animal sourcing reduces contamination risks.

Unparalleled insight into reprogramming mechanisms

Multidimensional characterization maps compositional determinants guiding cell state transitions. Machine learning models uncover obscure matrix-mediated effects invisible to humansLet's discuss how applying Matrix Bio's integrated solutions can help overcome significant bottlenecks constraining your viral reprogramming pipelines and platform capabilities. We welcome the opportunity to explore potential partnerships.


Please reach out at solutions@matrixbio.com to schedule an introductory call with our team.


We can share additional details on how advanced niches engineered using our proprietary workflow can enhance efficiency, scale, and control for your critical cell engineering needs.

AI-Assisted Design Tools

Predict a hydrogel's mechanical properties, generate new formulations with optimal swelling ratios, enhance cell compatibility, and much more on the horizon

Mechanical properties prediction

Predict the mechanical behavior of your individual or composite hydrogel with our AI tools. Designed for speed without sacrificing accuracy.

Name: Alginate-Gelatin Composite

Variant: variant1 osteogenic functionality

Swelling Ratio

Tune the swelling ratio of your hydrogels with models trained on extensive datasets. Achieve even more precise predictions after a round of lab experiments.

Biocompatibility

Optimize your hydrogel’s properties for enhanced cell attachment and proliferation. Go beyond standard metrics and utilize machine learning models trained on biocompatibility data from diverse contexts.

  • Durability

Engineer hydrogels that withstand harsh conditions by improving their durability.

  • Bioactivity

Engineer hydrogels that withstand harsh conditions by improving their durability.

  • Adhesion

Design hydrogels with optimal adhesion properties for tailored applications.

  • Porosity

Fine-tune your hydrogel's porosity for controlled substance transport.

  • Multi-objective

Optimize multiple performance criteria simultaneously by setting targets for diverse properties and let our models find the optimal balanc

Swelling Ratio

Tune the swelling ratio of your hydrogels with models trained on extensive datasets. Achieve even more precise predictions after a round of lab experiments.

Biocompatibility

Optimize your hydrogel’s properties for enhanced cell attachment and proliferation. Go beyond standard metrics and utilize machine learning models trained on biocompatibility data from diverse contexts.

  • Durability

Engineer hydrogels that withstand harsh conditions by improving their durability.

  • Bioactivity

Engineer hydrogels that withstand harsh conditions by improving their durability.

  • Adhesion

Design hydrogels with optimal adhesion properties for tailored applications.

  • Porosity

Fine-tune your hydrogel's porosity for controlled substance transport.

  • Multi-objective

Optimize multiple performance criteria simultaneously by setting targets for diverse properties and let our models find the optimal balanc

Private.
Secure.
Yours.

Matrix Bio safeguards your formulation data while granting you complete ownership of all intellectual property.

Private by design

We acknowledge the invaluable nature of your formulation data, and we commit to its privacy. Access to data is strictly limited to you and the members of your organization.

Safe & secure

With extensive industry experience, we prioritize security. Matrix Bio uses bank-grade security measures to protect your data.

Own your IP

We make IP ownership straightforward. You own the IP, no royalty issues. You simply pay for usage of our platform and tools.